Little Armenia is located in East Hollywood below Beachwood Canyon and Los Feliz. The area is bounded on the north by Hollywood Boulevard between the 101 Freeway and Vermont Avenue, on the east by Vermont Avenue from Hollywood Boulevard to Santa Monica Boulevard, on the south by Santa Monica Boulevard between Vermont Avenue and U.S. Route 101 and on the west by Route 101 from Santa Monica Boulevard to Hollywood Boulevard".

In 1999, the Honorary Mayor of Little Armenia, Garbis Keurjikian, also known as Garo, had a vision to establish an area in East Hollywood representing the Armenians who migrated to America. On October 6, 2000, the Los Angeles City Council designated a portion of East Hollywood as “Little Armenia” in an effort to recognize the community’s vast “presence and voice in Los Angeles.”

St. Garabed Armenian Apostolic Church is an Armenian church that is located inside Little Armenia. St. Garabed church is the place of worship for the vast majority of Armenians living in Hollywood. It is located on Alexandria Avenue and it was built in 1978. The church is located in front of the Rose and Alex Pilibos Armenian School.

On April 24 each year, Armenians gather in Hollywood to commemorate the Armenian genocide.